pentobarbital will lower the extent or effect of saxagliptin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unfamiliar.pentobarbital will minimize the level or influence of dapsone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unknown.Use Caution/Check. CYP3A4 inducers might boost the met